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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPB49 All Species: 13.64
Human Site: S28 Identified Species: 42.86
UniProt: Q08495 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08495 NP_001107607.1 405 45514 S28 S S V P G S P S S I V A K M D
Chimpanzee Pan troglodytes XP_001151887 390 43947 S28 S S V P G S P S S I V A K M D
Rhesus Macaque Macaca mulatta XP_001101612 406 45710 S28 S S V P G S P S S I V A K M D
Dog Lupus familis XP_543258 401 44811 D31 S S I V A K M D N Q V L G Y K
Cat Felis silvestris
Mouse Mus musculus Q9WV69 405 45450 S28 S S V P G S P S S I V A K M D
Rat Rattus norvegicus Q6KC51 612 67991 C27 T A I L C N T C G N V C K G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513734 903 101324 H455 S I P G S P G H T I Y A K V D
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001107788 693 78810 R306 H S P R G E E R Q R P T R S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.3 95.5 95.8 N.A. 96 24 N.A. 21.9 N.A. N.A. 25.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.3 96.3 97.2 N.A. 98.2 34.4 N.A. 31.4 N.A. N.A. 36.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 20 N.A. 100 13.3 N.A. 33.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 100 46.6 N.A. 46.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 13 0 0 0 0 0 0 63 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 13 0 0 0 13 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 63 % D
% Glu: 0 0 0 0 0 13 13 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 63 0 13 0 13 0 0 0 13 13 0 % G
% His: 13 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % H
% Ile: 0 13 25 0 0 0 0 0 0 63 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 13 0 0 0 0 0 0 75 0 13 % K
% Leu: 0 0 0 13 0 0 0 0 0 0 0 13 0 0 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 13 0 0 13 13 0 0 0 0 0 % N
% Pro: 0 0 25 50 0 13 50 0 0 0 13 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 13 0 0 0 0 0 % Q
% Arg: 0 0 0 13 0 0 0 13 0 13 0 0 13 0 0 % R
% Ser: 75 75 0 0 13 50 0 50 50 0 0 0 0 13 13 % S
% Thr: 13 0 0 0 0 0 13 0 13 0 0 13 0 0 0 % T
% Val: 0 0 50 13 0 0 0 0 0 0 75 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _